Profile - Older Australian Twins Study (OATS)
The Older Australian Twins Study (OATS) aims to examine genetic and environmental factors for cognitive decline and dementia in late life. We are a multi-centre, longitudinal study incorporating identical and non-identical twin pairs aged 65 years and older. Baseline, two-year and four-year follow-up data have been collected on a wide range of parameters. Participants have undergone rigorous medical and cognitive function tests, provide blood samples and have a MRI scan of their brain. Information about environmental factors, such as medical and psychosocial history, lifetime physical and mental activity, falls and cardiovascular history, and nutrition has also been collected. Data from the study has made significant contributions to understanding the genetic versus environmental factors underlying aspects of cognition, brain structure, and the role of proteins in healthy ageing. MRI and blood data has contributed to understanding the heritability of brain structure and function, the role of brain metabolites, and the epigenetics of memory and learning. Current work is utilising the longitudinal data to progress research in these fields. We are continually seeking novel opportunities for collaboration to further research into healthy ageing. If you would like further information please contact, Jocelyn Bowden, OATS Study Coordinator on email@example.com, or visit our website at cheba.unsw.edu.au/project/older-australian-twins-study.