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Newsletter #121
January 25th, 2018
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Editorial

As 2018 gets rolling, the Gut Microbiota for Health team is looking forward to tracking the developments to come in gut microbiota science. At this stage we're also looking back -- because we're pleased to be celebrating our 5-year anniversary! In this newsletter, check out the short video about our achievements and where the Gut Microbiota for Health community stands today.

This newsletter continues with an article by GMFH scientific board member Patrice D. Cani, who gives an overview of the mechanisms of action of both traditional and next-generation probiotics. Next, we give you one of the first detailed reports on how salt affects gut microbiota and health -- a report that found (in mice) a high salt diet depletes lactobacilli in the gut and may contribute to disease-related immune dysfunction.

Turning to clinical studies, we share with you a new meta-analysis of 53 trials covering the latest evidence for weight manipulation through interventions that target the gut microbiota: prebiotics, probiotics, synbiotics, and antibiotics. Finally, we bring you a review on how gut microbiota could mediate the effects of nutrition on sarcopenia and frailty in older adults.

We hope to see you at the Gut Microbiota for Health World Summit 2018, March 10th and 11th -- and if you can't make it in person, be sure to mark your calendar and follow along on Twitter using #GMFH2018!

The GMFH publishing team

#GMFH5years: A video tracking 5 years of education on gut microbiota and health
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A brief overview of the mechanisms of action by which traditional and next-generation probiotics affect host health


Probiotics have a range of documented effects on human health, with hundreds of studies from the past several decades showing their ability to alter physical or behavioural phenotypes in humans. These human efficacy trials provide...


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Salt depletes lactobacilli in the gut and may be partly involved in autoimmune- and hypertension-linked immune dysfunction


Recent research has explored how specific dietary components such as proteins, fats, carbohydrates, probiotics and polyphenols interact with the gut microbiome to confer health benefits on the host. Although high salt content in the Western...


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A new review covers current scientific evidence for weight manipulation through targeting the gut microbiota


Previous evidence from both mouse models and humans has suggested that manipulation of the gut microbiota could help us understand how to deal with the current global obesity epidemic. However, whether the effects of targeting...


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Gut microbiota could mediate the effects of nutrition on sarcopenia and physical frailty in older populations


Human ageing is characterized by a chronic low-grade inflammation, termed “inflammaging”, that together with sarcopenia (muscle mass depletion and the reduction of muscle performance) and physical frailty (the loss of muscle performance and normal muscle...


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