Georgia Prevention Institute 



Making a Difference in Health and Healthcare

Mission: To improve health and healthcare across the lifespan through Research, Education, and Service.

New Manuscripts Published

BH4 improves postprandial endothelial function following a high-fat meal in man and post-menopausal women.

Shah, Y, L. Bass; G.W. Davison; N. Seigler; J.S. Pollock; J. Thomas; R.A. Harris.

Objective.  The timing and duration of menopause is important when evaluating the risk for cardiovascular disease (CVD) in postmenopausal women, likely related in part to nitric oxide (NO) bioavailability.  The flow mediated dilation (FMD) test is a non-invasive assessment of NO bioavailability in humans, and tetrahydrobiopterin (BH4) is essential for NO synthesis.  A high-fat meal (HFM) has been used to increase lipemia and reduce NO-bioavailability.  Thus, this study sought to determine if menopausal transition has any impact on the postprandial endothelial function response to a HFM and evaluate the effect of BH4 on postprandial endothelial function in postmenopausal women and men. Conclusions.  Co-ingestion of BH4 with a HFM not only alters the sex-steroid hormone ratio, it improves postprandial FMD following a HFM regardless of postmenopausal status or sex.

Full text not yet avaliable. This will be a "Menopause. In Press" publication. 
See full Abtract
How lateral inhibition and fast retinogeniculo-cortical oscillations create vision: A new hypothesis.

Ravinder Jerath; Shannon M. Cearley; Vernon A. Barnes, Elizabeth Nixon-Shapiro.

Objective: The role of the physiological processes involved in human vision escapes clarification in current literature. Many unanswered questions about vision include: 1) whether there is more to lateral inhibition than previously proposed, 2) the role of the discs in rods and cones, 3) how inverted images on the retina are converted to erect images for visual perception, 4) what portion of the image formed on the retina is actually processed in the brain, 5) the reason we have an after-image with antagonistic colors, and 6) how we remember space. This theoretical article attempts to clarify some of the physiological processes involved with human vision. Conclusion: Our theory suggests image inversion never takes place on the retina, but rather images fall onto the retina as compressed and coiled, then amplified through lateral inhibition through intensification and amplification on the OFF-center cones. The intensified and amplified images are decompressed and expanded in the brain, which become the images we perceive as external vision.
See Manuscript

Upcoming Abstract Presentations

Braselton, GA - October 21-23, 2016
*Aarthi Murugappan, Anas Raed, Deborah Stewart, and Yanbin Dong. "Association of AST/ALT Ratio and Metabolic Syndrome in Southeast United States Hispanic Farm Workers" 
*Congratulations to Aarthi Murugappan, one of Bin's medical scholar students on being accepted to provide a poster presentation in the GAACP Abstract Competition on October 21st!

Scientific Session 2016
New Orleans, Louisiana- November 14th
"Effect of Changing Sodium Intake on miRNA Profiling in Hypertensives" ~Haidong Zhu, Fengjun He, Justin Choi, Yanbin Dong and Gregory A. Harshfield. This work is in collaboration with Queen Mary University of London.

Shaoyong Su, Guang Hao, Frank Treiber, Gregory Harshfield, Xiaoling Wang. Impact of Childhood Adversities on Blood Pressure Regulation in Real Life: Results From a 23-Year Longitudinal Study Through Childhood to Young Adulthood. 

*Guang Hao, Xiaoling Wang, Frank Treiber, Gregory Harshfield, Gaston Kapuku, Shaoyong Su. Blood Pressure Trajectories, Carotid Artery Intima-Media Thickness and Left Ventricular Mass: Results From a 23-Year Longitudinal Study From Childhood to Young Adulthood. 
*Guang Hao, PhD is a post doc for Shaoyong Su, PhD

We are Famous! 

We made front page news in the Augusta Chronicle!
Featuring Gregory Harshfield, PhD & Haidong Zhu, PhD.
Take home message: Lower sodium diets can reduce blood pressure! It is also important to make healthy choices early in life. Click on the 
article link and scroll to the bottom to see the comments and questions from members in our community. Click

Thanks to Kim Norland, Nichole Lee and the rest of the event committee for making this a fun day for everyone!


Celebrating New Life

Olivia Allyn Lee is expected around December 7th to her new parents to be, Wil and Nichole Lee. GPI helps them celebrate this special occasion! Thanks to the GPI event committee for making this a great experience! 

Call for Abstracts

American Psychosomatic Society.Mobilizing Technology to Advance Biobehavioral Science and Health. This is the 75th Anniversary Annual Scientific Meeting of the American Psychosomatic Society. Meeting takes place in Sevilla, Spain March 15-18, 2017. Abstracts due October, 20th 2016. 

American College of Sports Medicine Annual Meeting. 
ACSM's 64th Annual Meeting, 8th World Congress on Exercise is Medicine® and World Congress on the Basic Science of Exercise and the Brain. Meeting is held in Denver, Colorado May 30th-Jun 3rd. Now accepting abstracts. Abstracts due Nov 1st 2016.

Events in October


As in previous years,
the GPI has put together a team for the USG health fitness initiative.  You all should have received your invitation to join the team!  Please register here: and start recording your fitness today.  Help us reach our goal
and show the university what GPI is all about!

Trick-or-Treat Birthday Celebration - Monday, October 31st @ 12:30pm.

Bring your best Halloween themed dish for a wonderfully ghoulish time!

Wear your best costume and decorate your cube or office door as the kids of the Augusta University Childcare Center trick-or-treat with us on Monday,
October 31st @ 9:30am.
Please provide healthy items if possible. Examples include pretzels, play dough, and puzzles.

Prize will be awarded to the best decorated door or cubicle.

Vishal Doshi- October 2nd
Maudesta Caleb-October 4th
Xin Wang-October 20th
Kim Norland-October 22nd
Katie Davis-October 28th
Yue Pan-October 29th

Please give us your feedback

What would you like to see in upcoming issues of the GPI bulletin? 
Tell us how we can improve. 

James Halbert, MS
 Deborah Stewart, BS

Copyright © 2016  Georgia Prevention Institute, All rights reserved.

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Population Health Sciences / Augusta University · 1120 Walton Way · HS-1755 · Augusta, GA 30919 · USA

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