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Georgia Prevention Institute Bulletin

May your days be merry and bright!

We have a special gift just for you! To open click on the present below.

Published Manuscripts

Outcomes Following Routine Antithrombin III Replacement during Neonatal Extracorporeal Membrane Oxygenation

Brian K. Stansfield; Linda Wise; P. Benson Ham III; Pinkal Patel; Malinda Parman; Chan Jin; Sunil Mathur; Gregory Harshfield; Jatinder Bhatia

Background: We sought to examine the effect of routine Antithrombin III (AT3) infusion on hemorrhagic and thrombotic complications, blood product utilization, and circuit lifespan in neonatal extracorporeal membrane oxygenation (ECMO). Conclusion: Routine administration of AT3 in neonates receiving ECMO therapy was associated with tighter control of anticoagulation and a reduction in thrombotic events without increasing unwanted bleeding. However, circuit lifespan was unaffected.

This is a "Journal of Pediatric Surgery" publication.
See Full Manuscript
Blood pressure trajectories from childhood to young adulthood associated with cardiovascular risk: Results from the 23-year longitudinal Georgia Stress and Heart study

Guang Hao, MD, PhD, Xiaoling Wang, MD, PhD, Frank A. Treiber, PhD, Gregory Harshfield, PhD, Gaston Kapuku, MD, PhD, Shaoyong Su, PhD 

Objective: To identify subgroups of individuals with similar trajectories in blood pressure (BP) from childhood to young adulthood, and to determine the relationship of BP trajectories with carotid intima-media thickness (IMT) and left ventricular mass index (LVMI). Conclusion: We for the first time reported the association between SBP trajectories derived from childhood with subclinical cardiovascular risk in young adulthood, indicating that monitoring trajectories of BP from childhood may help identify a high cardiovascular risk population in early life.

Manuscript not yet ready, please see abstract. This will be a "Hypertension" publication.
See Full Abstract


Growth of carotid intima-media thickness in African American and European American young adults

Guang Hao, MD, PhD, Xiaoling Wang, MD, PhD, Frank A. Treiber, PhD, Harry Davis, MS, Sharika Leverett, BS, Shaoyong Su, PhD,  Gaston Kapuku, MD, PhD

Background: There are few longitudinal studies that have comprehensively examined the IMT growth pattern and its risk factors among ethnic population groups. Conclusion: Our findings provide compelling prospective evidence that AAs may have thicker IMT compared to EAs as young adults.  These ethnic differences could not be explained by traditional risk factors.  This implies that differences in precursor of atherosclerosis may explain ethnic disparity in cerebrovascular disease.

Manuscript not yet ready, please see abstract. This will be a "Journal of the American Heart Association" publication.
See Full Abstract

Skeletal Muscle Oxidative Capacity is Altered in Patients with Cystic Fibrosis

Paula Rodriguez-Miguelez, Melissa L. Erickson, Kevin K. McCully, Ryan A. Harris

Exercise intolerance has been shown to predict mortality in patients with cystic fibrosis (CF) independent of lung function. Despite the clinical importance for assessing exercise capacity, the mechanisms which lead to exercise intolerance in CF have yet to be elucidated. Although evidence suggests that the impaired expression of CFTR in skeletal muscle may be associated with abnormalities in muscle oxygenation and muscle metabolism, there are recent studies that have described a preserved muscle metabolism in patients with CF. Considering the available data from multiple in vitro and in vivo studies, we provide compelling evidences to support the existence of mitochondrial dysfunction, impaired mitochondrial bioenergetics, and altered skeletal muscle oxidative capacity in patients with cystic fibrosis.

Manuscript not yet ready, please look for the final paper in the next issue. This will be a "Journal of Physiology" publication.

GPI staying in the News

Norman Pollock, PhD is keeping busy with his research using vitamin K, which may reduce obese children’s risk of cardiovascular issues by helping improve insulin sensitivity and reducing lipid levels in their blood – both huge risks for, not only cardiovascular disease, but also diabetes. Peter Buckley, MD recognizes Dr. Pollock's achievements in the Deans Diary.  Last month we showed Dr. Pollock's media attention with the Augusta Chronicle. His achievements are also spreading to different news organizations such as News Medical. 
In the News
Shaoyong Su, PhD is also in the news with his research on early life stress and its impact on blood pressure later in life. HealthDay: "News for Healthier Living" picked up on his presentations at the annual American Heart Association's Scientific Session meeting in November, and wanted to spread the word to provide healthier futures for today's adolescents. He was also featured on the AHA Newsroom website in an interview about his presentation titled "Impact of childhood adversities on blood pressure regulation in real life: results from a 23-year longitudinal study from childhood through young adulthood".
HealthDay News
AHA Newsroom
Telomeres tell their tail! The length of your telemeres can show researchers how healthy your heart is. This study pays close attention to vitamin D, and omega-3. Yanbin Dong, PhD, MD and Haidong Zhu, PhD were featured in the JagWire. 
In the News


Our very own Maudesta Caleb, is graduating December 2016 with her Ed.S in Counselor Education. We are so proud of her, and her great achievement!!!
Dr. Yanbin Dong has joined the American Heart Association (AHA) CSRA Division Board of Directors. He will be working with an outstanding team of local experts to discuss and determine the priorities of the mission of the AHA, working to help them achieve the association's health and financial goals over the next two years.

Special Thanks!

Thanks to all the GPI event committee members who served in 2016! These people were responsible for all the birthdays gifts, spontaneous surprises, event decorations, and were our party organizers this year. 
Deborah Stewart
Abir Abdulbaki 
Amie Mangieri
Mary Ellen Fain
Allison Jasti
Kim Norland
Paula Rodrigues-Miguelez
James Halbert (J.D.)
Martha Tingen
Nichole Lee
Sandra Young-Mayes (Sandy)

If you'd like to become a member of the Event Committee for 2017, please see Deborah Stewart or JD Halbert.  Also, any suggestions or requests for event ideas are welcomed and greatly appreciated.

Way to go GPI!!!

Thank you to everyone who represented GPI and participated in the HealthTrails challenge! As a department, GPI completed 7,045.1 miles.

Team Name                       Miles Completed           USG Ranking            AU Ranking
Thundercats                              4009.0                            25                                 4
GPI Vikings                                2582.3                            59                                10
GPI Running on Empty              2567.5                            59                                10
HealthTrail Heroes                     2189.2                            88                                24
GPI Gym Class Heroes              2719.8                            93                                26
GPI Fire Ants                             2136.1                            127                               31
Special recognition goes to GPI Fire Ants and GPI Vikings for most improved teams!

Paula Rodriguez-Miguelez-December 2
Ying Huang -December 3
Nichole Lee -December 11th
Reva Crandal -December 12th

Special Event in December

Other Events in December

Holiday Luncheon - December 12th @ 12pm
White Elephant Gift Exchange - December 12th @ 1:30pm

GPI Annual Christmas Charity 

Don't forget our Annual Holiday Charity! This year, we have decided to partner with 88.3 WAFJ and Head of the Giant ministry to adopt two local families. Details of this charity were sent by a separate email. Help us make this Christmas extra special for these families in our community.  Please remember to have your contributions in by December 15th! 

Call for Abstracts

Society for Epidemiologic Research- Meeting in Seattle, Washington on June 20-23rd 2017. Accepting abstracts until January 17th 2017. Submit your abstract here

Please give us your feedback

What would you like to see in upcoming issues of the GPI bulletin? 
Tell us how we can improve. 
James Halbert, MS
 Deborah Stewart, BS
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Population Health Sciences / Augusta University · 1120 Walton Way · HS-1755 · Augusta, GA 30919 · USA

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