Georgia Prevention Institute
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Our bulletin's one year anniversary! The GPI bulletin has published some amazing things this past year, and this is all because we work with amazing people! Thanks for all you do!  

American Heart Association

It's not too late! Help us reach our goal! Don't forget the HeartWalk is on March 11th. This will be a great day for your family to get out and enjoy the Greeneway! Sign up to be a walker, then bring your family for a day of absolute fun!

To Join or donate click here!

Published Manuscripts 

One of the many rewarding aspects working at GPI is knowing the impact our research scientists have all over the world. These two publications were a collaborated effort from one our post-docs, Dr. Paula Rodrigues-Miguelez. Her efforts reach as far as Spain and Sweden.  

Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects
Yubisay Mejías-Peña, Brisamar Estébanez, Paula Rodriguez-Miguelez, Rodrigo Fernandez-Gonzalo, Mar Almar, José A. de Paz, Javier González-Gallego, María J. Cuevas
Objective: Aging is associated with a decline in autophagy and a state of low-grade inflammation which further affects apoptosis and autophagy. Importantly, these alterations could reverse with regular physical activity. This study assessed the effects of a resistance exercise training program on autophagy, NLRP3 inflammasome, and apoptosis in peripheral blood mononuclear cells (PBMCs) from elderly subjects. Results: The results obtained seem to indicate that 8-week resistance training stimulates autophagy, prevents NLRP3 inflammasome activation, and reduces apoptosis in PBMCs from elderly subjects. This data could have a significant impact in prevention and rehabilitation programs currently employed in the elderly population.
See Full Manuscript
Metabolic adaptations in skeletal muscle after 84 days of bed rest with and without concurrent flywheel resistance exercise.

José M. Irimia, Mario Guerrero, Paula Rodriguez-Miguelez, Joan A. Cadefau, Per A. Tesch, Roser Cussó, and Rodrigo Fernandez-Gonzalo

Objective: As metabolic changes in human skeletal muscle after long-term (simulated)spaceflight are not well understood, this study examined the effects of long-term microgravity, with and without concurrent resistance exercise, on skeletal muscle oxidative and glycolytic capacity. Conclusion: The proposed flywheel resistance exercise was effective in counteracting some of the metabolic alterations triggered by 84-day bed rest. Given the disparity between gene expression vs.enzyme activity in several key metabolic markers,post transcriptional mechanisms should be explored to fully evaluate metabolic adaptationsto long- term microgravity with/without exercise countermeasures in human skeletal muscle.
See Full Manuscript

Moving Forward

Anas Raed, MD, is finishing up his research residency. His last day at GPI is March 3rd. We wish him the best as he moves his focus into clinical work. Thanks Dr. Raed for all your great contributions to research and the GPI.   
Martha Tingen-March 7th
Abir Abdulbaki-March 13th
Jia Wang-March 17th
Greg Harshfield-March 22nd
Jacob Looney-March 24th

Events in March

Heart Walk March 11th
Lucky Leprechaun 17th
Semi-annual Birthday Lunch 21st


Call for Abstracts

American Heart Association: Council on Hypertension Scientific Sessions 2017 in San Francisco, Calif. at the Hyatt Regency September 14 – 17, 2017
Abstracts submission opens March 1st. 

The Obesity Society: Research. Education. Action. Obesity week 2017 is happening at Washington, DC metro area at the Gaylord National Resort & Convention Center in October. 
Abstract submission opens March 31st. 

The date is set and the challenge is about to begin! 
Register you and your team on March 1st and race to the top for fitness.  The challenge begins on March 20th.  For more information see .
James Halbert, MS
 Deborah Stewart, BS
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Population Health Sciences / Augusta University · 1120 Walton Way · HS-1755 · Augusta, GA 30919 · USA

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